Pressurised Metered-Dose Inhaler (pMDI) Production Systems
Location: Various, Worldwide
Scope: Overall process design and build of new pressurised Metered-Dose Inhaler (pMDI) production systems and associated HFA mixing vessels.
Briggs of Burton have been involved designing and building pressurised Metered-Dose Inhaler (pMDI) production systems. Briggs of Burton have provided a number of these systems to several major Pharmaceutical companies offering inhalers to relieve the symptoms of asthma and Chronic Obstructive Pulmonary Disease (COPD). Many of these projects used the bronchodilator Salbutamol as the Active Pharmaceutical Ingredient (API) that is suspended in a HFA-134a or HFA 227 based formulation, which would be transferred and filled into pressurised Metered Dose Inhalers (pMDI).
Several of these systems were built under Briggs of Burton’s Giusti brand and included the high pressure suspension preparation vessel, Drug Addition Vessel (DAV) and lift system, the HFA mixing vessels and supply pipework and overall control system.